Discover Medik8’s youth awakening masterpieces

Worth £435 (Plus a complimentary vanity case)

4 products



This Luxe Collection brings together the complete powerhouse of Medik8’s masterpiece range, providing the ultimate path to skin rejuvenation.

Groundbreaking science is interlaced with sublime formulations, so you can enjoy a beautiful sensorial experience with profound visible age-defying revitalisation.

Featuring a complimentary travel vanity case. Soft-touch, waterproof and durable, the elegant, reusable case has 3 large compartments to separate all your beauty must-haves.


Lines and wrinkles appear to vanish from sight, under-eyes are infused with vitality and radiance with the overall complexion left looking flawlessly illuminated.


The r-Retinoate Collection harnesses the age-defying powers of legendary retinyl retinoate to dramatically fade the appearance of lines and wrinkles. Active ingredients profoundly improve visible tone, texture and skin radiance.


Retinyl Retinoate, Encapsulated Retinaldehyde, Drone-Targeted Copper Peptide, Tetrahexyldecyl Ascorbate (Vitamin C), Hyaluronic Acid, Hesperidin and Caffeine.



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Transcend the Evidence of Time


r-Retinoate Day & Night (50ml)

Featuring breakthrough hybrid molecule, retinyl retinoate: 8x stronger than retinol,[1] the transformative power of this light day and night serum is truly profound. Not only can this exquisite vitamin A be uniquely used twice daily, but also now the new improved formula has the addition of stabilised vitamin C. This exceptional antioxidant compliments the power of retinyl retinoate, leaving skin looking bright, radiant and visibly youthful.

[1] H. Kim, Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008,15;16(12), pp 6387-93


r-Retinoate Day & Night Eye Serum (15ml)

The ultimate indulgence for delicate under-eyes. This featherlight day and night serum sinks effortlessly into the eye contours and harnesses the age-defying prowess of legendary retinyl retinoate.


r-Retinoate Intense (50ml)

This extraordinary molecule, retinyl retinoate, is twinned with crystal-stabilised retinaldehyde to deliver our most powerful anti-ageing product. 8x stronger than retinol and 11x times faster acting than retinol [2] for the ultimate in overnight rejuvenation. Blended with skin-optimised peptides and ceramides, this night cream-serum hybrid is the all encompassing nighttime ritual for the most demanding of skincare enthusiasts.


[2] G. Seigenthaler et al., Biochemical Journal, 1990, 268, pp 371-378


How to use it


After cleansing in the morning and evening, blend r-Retinoate Day & Night evenly across face, neck and décolletage.


After cleansing in the morning and evening, apply r-Retinoate Day & Night Eye Serum around the delicate eye area, being careful to avoid the eyelids.


After cleansing in the evening, massage evenly across the face, neck and décolletage.

r-Retinoate Intense should be phased in gradually as it contains retinaldehyde. Use twice a week for the first 2 weeks, every other night for the next 2 weeks, then every night.

Patch testing

Patch testing prior to use is advised. Refer to for an in-depth guide to patch testing.


  • Retinyl Retinoate

    8 times more powerful than retinol and stable both day and night, this non-irritating vitamin A helps to stimulate collagen synthesis and supports the regeneration of skin cells.


  • Encapsulated Retinaldehyde

    Proven to work up to 11 times faster than retinol, retinaldehyde is a revolutionary new form of vitamin A that targets fine lines and wrinkles, pigmentation and uneven skin texture.


  • Drone-Targeted Copper Peptide

    A collagen-supporting copper peptide encapsulated in a polymer system which dives through the layers of the skin to specifically target collagen-producing cells.


  • Tetrahexyldecyl Ascorbate (Vitamin C)

    An exceptional antioxidant, this stabilised form of vitamin C protects the skin from harmful free radicals while helping to stimulate collagen production for a youthful complexion.


  • Hesperidin

    Found naturally in citrus fruits, hesperidin improves blood circulation and strengthens capillary walls for brighter under eyes.


  • Caffeine

    Revitalising caffeine helps to reduce the size of blood vessels to diffuse the appearance of tired eyes.


  • Multi-Weight Hyaluronic Acid

    With a unique ability to attract and retain more than 1,000 times its own weight in water, hyaluronic acid draws moisture from the air into the skin to provide intense hydration.


What we choose not to include


Hear from the experts

“All ingredients are skillfully mixed in our UK labs. To ensure continued pre-manufacture freshness of our exclusive active ingredient, retinyl retinoate, is blended precisely into the finished formula creating a powerful yet beautifully elegant cream-serum: maximising anti-ageing results in every single bottle.”

Daniel Isaacs
Director of Research

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AVANA Cosmetic & Beauty Clinic is a professional, non surgical beauty clinic located in West London.


The collection is available only from our main address: No 10 Bond Street, Ealing Broadway, London,  W5 5AA

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